X-ray Accident, Germany (1983)
Accident scenario
      The X-irradiation accident occurred in 1983. The subject, born in 1940, was exposed on several days between 1 and 16 June 1983, when carrying out radiographic examinations with an X-ray source. He had not been exposed to therapeutic irradiation or cytostatics before, nor had he been treated or investigated with radionuclides. Because of a defect, the X-ray machine emitted radiation for about 3 seconds after it had been turned off. The voltage of the machine was 120-130 kV during radiography and 60 kV during the ‘postirradiation’ period. Measurements carried out by reconstruction with a phantom gave estimates of 6 Sv to the chest and 12 Sv to the right hand. The patient dose detected his exposure by observing erythema of his chest, right hand, and right arm, starting around 15 June 1983. Later, the right hand developed some strong skin damage and a stiffening, and both effects have persisted to date. The first sample of venous blood was taken on 4 July, i.e. 18 days after the last exposure.
Reference
      Scheid W, Weber J and Traut H: Chromosome aberrations induced in human lymphocytes by an X-radiation accident: results of a 4-year postirradiation analysis. Int. J. Radiat. Biol., 54: 395-402, 1988.
Chromosome aberration analysis
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Sample code Months past No. of cells Distribution of dicentrics
0 1 2 3 4 5 6 7 8 9 10
BD06 1 1,147 1,134 12 1
BD08 5 1,108 1,092 14 1 1
BD10 10 1,127 1,110 15 1 1
BD12 12 1,196 1,084 11 1
BD18 19 1,095 1,089 4 2
BD24 25 1,135 1,133 2
BD30 31 1,692 1,685 7
BD40 36 1,074 1,072 2
BD43 43 1,070 1,066 4
BD45 49 1,063 1,058 5
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