| Accident scenario |
| A chromosomal study of a heavily irradiated
young Algerian boy is reported here. The boy was accidentally exposed to
gamma-rays from a 25 Ci iridium-192 source in May 1978. The manipulation
of the source induced a high irradiation of both hands, making necessary
the grafting of abdominal skin. |
| Chromosomal dosimetry |
| The cytogenetic study of skin fibroblasts
from a young boy, heavily irradiated handling of an iridium-192 source
of 25 curies is reported. About half of the cells examined had chromosomal
abnormalities. The same clone, with multiple chromosome rearrangement,
was observed in cultures from biopsies obtained 25 and 35 months after
the accident. Several other clones were detected in vitro. The results
obtained from cultures of biopsies from different locations show that no
direct relationships were found between the absorbed dose and the stable
chromosomal rearrangements. |
| Reference |
| Mouthuy M and Dutrillaux B: Cytogenetic study
of skin fibroblasts in a case of accidental acute irradiation. Mutation
Res., 95: 19-30, 1982. |
| Chromosome aberration analysis |
