4.9 MeV Protons

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	4.9 MeV protons
	Cyclotron: Kyoto University Cyclotron Laboratory																¤ Irradiation system
	Materials: Human peripheral blood lymphocytes (whole blood)																¤ Sample preparation
	[1] No magnetic field
	Dose	No. of	No. of	Distribution of cells with indicated number of dicentrics
	(Gy)	cells	Dics	0	1	2	3	4	5	6	7	8	9	10	11	≧12
	0.16	150	7	144	5	1
	0.33	500	75	432	62	5	1
	0.41	400	77	333	58	8	1
	0.51	850	145	723	109	18
	0.99	394	125	298	72	19	5
	1.01	600	240	407	152	36	4	1
	1.48	229	155	121	71	28	8	1
	1.97	130	188	38	43	22	17	3	5	1	1
	2	303	342	107	105	54	23	10	4
	2.5	324	482	97	91	70	39	10	9	7	1
	3	104	267	9	23	25	20	13	7	4	1	2
	3.1	81	148	16	23	20	10	6	5	1
	[2] Under magnetic field (1 Tesla)
	Dose	No. of	No. of	Distribution of cells with indicated number of dicentrics
	(Gy)	cells	Dics	0	1	2	3	4	5	6	7	8	9	10	11	≧12
	0.33	200	36	171	23	5	1
	0.41	200	62	147	44	9
	1.01	197	129	102	65	26	4
	1.48	209	183	95	70	27	9	8
	2.00	117	131	46	37	16	12	4	2
	2.50	111	203	21	31	27	15	13	3	1
	3.00	44	113	7	10	6	6	6	6	2	1
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	References: Takatsuji, T. et al. (1983) Induction of chromosome aberrations by 4.9 MeV protons in human lymphocytes. Int. J. Radiat. Biol., 44:553-562.
	Takatsuji, T. et al. (1989) Effect of static mahnetic field on the induction of chromosome aberrations by 4.9 MeV protons and 23 MeV
		alpha particles. J. Radiat. Res., 30:238-246.
		Takatsuji, T. et al. (1999) Generalized concept of the LET-RBE relationship of radiation-induced chromosome aberration and cell death.
		J. Radiat. Res., 40:59-69.																			.
		Sasaki, M. S., Takatsuji, T. and Ejima, Y. (1998), Radiat. Res., 150:253-258.
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